For the last 9 years or so, ever since my first visits to gyms and sports halls, i couldn’t help but notice that 70 percent of muscular guys who were in these gyms were either bald, balding, or very receding. This spiked my interest at an early age to find out what preventions there were , and what could be done to help cause regrowth of lost hair.
Enter the famous DHT blockers, with an astounding array of nasty sides, I know there has to be something better!!
Well through my studies i came across a few surprising alternitive therapies.
The main reason why lots of people get receeding hair lines, thinning hair and baldness is actualy caused by a lack of blood flow to the scalp..add that to the reduced size of the follicles caused by the conversion of DHT and then it binding to the skin and you have a recipe for hair loss.
So what can be done?
Well firstly i looked at vasolidators not prostaglandins, i wanted to look at products that contained the NO chemical analog.. Nitric oxide.reason being is that NO causes blood vessels to relax then It opens them up, promoting easy blood flow. Accordingly, NO is also referred to as endothelium-derived relaxing factor (EDRF). NO is a ubiquitous messenger with far-reaching effects in the body, Suprisingly minoxidil contains the NO chemical group, Just look at its name! miNOxidil. Now NO is involved in opening potassium channels, also known as the K-channels, so more blood flow to the follicles =more nutrients delivered and more stimulation of the follicle.. so this is a great start.
So the product ive been looking at is the amino acid L-arginine, its got great potential as a toplical blood flow enhancer, its just 174.2 daltons, thats its molecular weight so making it a transdermal is very possible. And its a very active precursor to NO!
The next ingredient i looked at was caffeine, its been used topicaly for hundreds of years in some cultures to stimulate healing… well if we look at balding as a wound, caused by a lack of circulation then it looks like caffeine might help, but how?
Well firstly here is a study conducted by the University of jena in germany.
Research carried out at the Department of Dermatology and Allergology, at the Univeristy of Jena, in Germany, studied the effects of both caffeineand testosterone on in vitro hair follicle samples.The research aimed to determine the affect of both these substances on androgenetic alopecia and (AGA), a form of hereditary hair loss. This condition affects 50 per cent of men aged 50 years old and currently feeds a huge industry that includes topical, oral and surgical treatments.
The research found that caffeine application spurred growth, while testosterone clearly impeded growth.
Hair follicles from 14 biopsies were taken from the top of the scull of male patients and the samples were cultivated for 120hrs to 192hrs, with hair shaft elongation measured on a daily basis and at the end of the test period.
The results showed significant growth suppression in hair follicles treated with 5 micro grams per milliliter. This was countered by caffeine tested in concentrations of 0.0001 per cent and 0.005 per cent.
The researchers said that, on the contrary, caffeine significantly boosted growth of the hair follicles, leading the team to conclude that caffeine is a stimulator of hair growth and ‘may have important clinical impact in the management of AGA’
It seems that caffeine actualy stimulates blood flow to the follicles and impedes the effects that Testosterone has on downsizing the follicle, causing the hair shaft to become thinner, as Caffeine regultes testosterone so well, its future looks bright, but topicaly not oraly is the way to go.
Next i looked at alternative DHT blockers.. no not saw palmetto.. something better.
Banana peel extract, no im not joking though it could be why monkeys are so hairy!
A methanol extract of banana peel (BPEx, 200 mg/kg, p.o.) significantly suppressed the regrowth of ventral prostates and seminal vesicles induced by testosterone in castrated mice. Further studies in the androgen-responsive LNCaP human prostate cancer cell line showed that BPEx inhibited dose-dependently testosterone-induced cell growth, while the inhibitory activities of BPEx did not appear against dehydrotestosterone-induced cell growth. These results indicate that methanol extract of banana peel can inhibit 5alpha-reductase and might be useful in the treatment of benign prostate hyperlasia.. Whats interesting is that it seems its more effective than saw palmetto at this.
The other one i looked at was Equol (7-hydroxy-3[4’hydroxyphenyl]-chroman) is the major metabolite of the phytoestrogen daidzein, one of the main isoflavones found abundantly in soybeans and soy foods.. The reason this is interesting is because of its unique action on DHT.
This is the magic part.
equol specifically binds 5alpha-dihydrotestosterone (DHT), but not testosterone, dehydroepiandrosterone, or estrogen with high affinity. Equol does not bind the prostatic androgen receptor, and has a modest affinity for recombinant estrogen receptor (ER) beta, and no affinity for ERalpha. In castrated male rats treated with DHT, concomitant treatment with equol blocked DHT’s trophic effects on the ventral prostate gland growth and inhibitory feedback effects on plasma LH levels without changes in circulating DHT. Therefore, equol can bind circulating DHT and sequester it from the androgen receptor, thus altering growth and physiological hormone responses that are regulated by androgens. So You still recieve the benefits of DHT but not in the androgen receptor of the skin primarily.
Now the exciting part is that i combined these ingredients.. and i found something very interesting, One person who recently lost hair after using Masteron Tren and Test, regained 80 percent of his hair on the hair line, Now in the process of carrying out a study on somone with MPB that he has had exert its affects since he was 17, now at the age of 37 he is nearly completely bald… My anticipation is building to see the results.
In the meantime, look for shampoos containing caffeine… And keep positive, this a a hugely under invested, and under studied area, breakthroughs are coming… combining the above ingredients and the positive effects of GHRH analogs like cjc-1295, and GHRP’s like ipamorelin seems to be the way to go, as both of these increase blood flow, and your healing hormone GH.. as GH opens the potassium channels.
My research will continue, if you enjoy reading please post a comment, any donations are accepted.
Kind regards Russianstar.