ATD a potent anti-oestrogen

3,17-dioxo-etiochol-1,4,6-triene
1,4,6-Androstatrien-3,17-dione
1,4,6 etiollochan-dione
Known as: ATD
Half life : 48 hours
Molar mass: 282
What is ATD?
1,4,6-Androstatrien-3,17-dione (ATD) is a potent irreversible A.I that inhibits estrogen biosynthesis by permanently binding and inactivating the Aromatase enzyme in the adipose tissue, (Fat cells) and in the surrounding peripheral tissue.
It can be used on cycle and during PCT to reduce estrogen and help recover natural testosterone production.
ATD has 90% androgenic activity in muscle tissue but only 10% androgenic activity in the hypothalamus. What this means is it helps you hold onto muscle and it also means that ATD blocks the Androgen-Negative-Feed-Back-Loop and aids in decreasing estrogen production while increasing natural testosterone production. Used on cycle it should help reduce shutdown, and prevent estrogen related sides.
How does it work?
There are two main negative feedback loops that we need to consider in PCT. The first is elevated estrogen levels from aromatase activity that will act on the hypothalamus to decrease GnRH production. The second is that elevated androgen levels stimulate androgen receptors in the hypothalamus causing decreased GnRH production. Decreased GnRH leads to reduced LH and FSH production, both of which are directly involved in testosterone production.
ATD combats this in a very interesting way.
ATD works for androgen activity the same way that Serm’s like Nolvadex block estrogen in breast tissue, but allows estrogen to have positive effects in other organs and tissues such as the liver and bone. ATD blocks androgens in the hypothalamus, but allows it to be active in the muscle, By doing this it increases GnRH production, increasing LH and FSH leading to increased testosterone.
ATD also lowers estrogen and is therefore able to increase GnRH from that angle also.
This is how it tricks your body into producing more testosterone.
How can it be used?
Obviously it can be used in PCT, but it has therapeutic affects on cycle, first it only has Anti-androgen affects in the hypothalamus, this means that along with it not interfering with any positive affects from AAS, it also means less shutdown as the androgenic or estrogenic affects of steroids are unable to cause shutdown in the same way as they would without ATD.
As it prevents estrogen and androgens from shutting down GnRH production, less HTPA shutdown takes place, and so recovery after stopping the steroid cycle is much easier.
What does is affective?
25mg a day of ATD on cycle will prevent a large measure of shutdown, obviously depending on what AAS are being used, higher amounts than this can cause severe joint pains and dryness..
During PCT you will notice a surge in libido and then libido drop off, so I suggest starting at 50mg a day, then tapering off this allows for estrogen and androgen levels to return to homeostatis, and it will also prevent estrogen or androgen rebound, prevent Acne and estrogen related rebound sides.
Points of interest.
ATD will give a positive sample as its metabolites are similar to that of the vetinary steroid Equipoise, so please keep this in mind.
Kindest regards Russianstar.
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